Physiotherapy interventions for enhancing neuroplasticity in people with spinal cord injuries: A systematic review of randomized control trials
Abstract
A systematic review of randomized control trials was conducted to provide an overview of the effectiveness of physiotherapy interventions for enhancing neuroplasticity and by extension functional recovery in people with SCI.
The appropriate MESH keywords were used in September of 2022 to search the global databases: PubMed, Science Direct, Cochrane and Scopus. In the review, only randomized controlled trials (RCTs) were included, which met the inclusion and exclusion criteria. The RCTs that were included in this review evaluate the effect of different physiotherapy interventions on neuroplasticity in people with spinal cord injuries. All studies were assessed for risk of bias using the Pedro scale.
In our study, we included 6 randomized control trials. Interventions such as massed practice with somatosensory stimulation, exercise with corticospinal neural stimulation, endurance training, intermittent hypoxia (IH) combined with Body weight supported treadmill training and paired transcranial direct current stimulation (tDCS) with Locomotor training with a robot-assisted gait orthosis (LT-RGO) were shown to enhance neuroplasticity and induce functional recovery in people with SCI. Therefore, further research needs to be done.
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