Vitamin D and musculoskeletal health

  • S Tournis Laboratory for Research of the Musculoskeletal System (LRMS) “Th. Garofalidis”, School of Medicine, University of Athens, Greece
  • K Liosis 5th Orthopaedic Department, HYGEIA Private Hospital, Athens, Greece
  • V Samdanis 5th Orthopaedic Department, HYGEIA Private Hospital, Athens, Greece
  • M Makestas 5th Orthopaedic Department, HYGEIA Private Hospital, Athens, Greece
  • I.K. Triantafyllopoulos 5th Orthopaedic Department, HYGEIA Private Hospital, Athens, Greece
Keywords: Vitamin D ; Metabolic bone disorders ; Musculoskeletal health


Vitamin D is a steroid pro-hormone, with effects that are not limited to the metabolism of calcium and phosphorus, but are pleiotropic and involve cellular differentiation, the immune response, intermediate metabolism and the cardiovascular system. This fat-soluble vitamin plays a significant role in musculoskeletal homeostasis and its deficiency or mal-regulatory function leads to several bone metabolic disorders.


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