Osteoporotic vertebral compression fractures: The effect of Vertebroplasty and Kyphoplasty including local kyphosis correction on pain relief
Keywords:
Vertebral fractures; Osteoporosis; Vertebroplasty; Kyphoplasty
Abstract
Vertebral compression fractures (VCFs) are the most common complication of osteoporosis. Most of the times VCFs lead the patients to the health care system because of the severe pain and many of them require surgical approaches for pain relief. Percutaneous vertebroplasty (PVP) and balloon kyphoplasty (BK) represent two surgical procedures involving percutaneous injection of bone cement into a collapsed vertebra. The aim of these two techniques is to restore vertebral height and to provide pain relief. Percutaneous vertebroplasty may provide correction of the local kyphosis, however it does not seem to play an important role on pain relief. We reviewed reports of these two procedures in patients with osteoporosis. Most of the case reports suggested that an over 67% relief of patients symptoms, but there are also complications which are relative to these methods. Some of these complications include new VCFs in adjacent adjacent levels as well as pain due to cement extravasation.
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References
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2. Watts NB, Harris ST, Genant HK. Treatment of Painful Osteoporotic Vertebral Fractures with Percutaneous Vertebroplasty or Kyphoplasty. Osteoporosis International 2001; 12:429–437
3. Rousing R, Hansen KL, Andersen MO, et al. Twelve-Months Follow-up in Forty-Nine Patients With Acute/Semiacute Osteoporotic Vertebral Fractures Treated Conservatively or With Percutaneous Vertebroplasty. SPINE 2010; 35:478–482
4. Rousing R, Andersen MO, Jespersen SM, et al. Percutaneous Vertebroplasty Compared to Conservative Treatment in Patients With Painful Acute or Subacute Osteoporotic Vertebral Fractures: Three-Months Follow-up in a Clinical Randomized Study. SPINE 2009; 34:1349–1354
5. Hinde K,. Maingard J, Hirsch JA, et al. Mortality Outcomes of Vertebral Augmentation (Vertebroplasty and/or Balloon Kyphoplasty) for Osteoporotic Vertebral Compression Fractures: A Systematic Review and Meta-Analysis. Radiology 2020; 00:1–8
6. Garfin SR, Yuan HA, Reiley MA. New Technologies in Spine: Kyphoplasty and Vertebroplasty for the Treatment of Painful Osteoporotic Compression Fractures. SPINE 2001; 26:1511–1515
7. Voormolen MHJ, Mali WPTM, Lohle PNM, et al. Percutaneous Vertebroplasty Compared with Optimal Pain Medication Treatment: Short-Term Clinical Outcome of Patients with Subacute or Chronic Painful Osteoporotic Vertebral Compression Fractures. The VERTOS Study. American Journal of Neuroradiology 2007; 28:555– 60
8. Winking M, Stahl JP, Oertel M, et al. Treatment of pain from osteoporotic vertebral collapse by percutaneous PMMA vertebroplasty. Acta Neurochirurgica (Wien) 2004; 146: 469–476
9. Voormolen MHJ, van Rooij WJ, Sluzewski M, et al. Pain Response in the First Trimester after Percutaneous Vertebroplasty in Patients with Osteoporotic Vertebral Compression Fractures with or without Bone Marrow Edema. American Journal of Neuroradiology 2006; 27:1579–85
10. Blasco J, Martinez-Ferrer A, Macho J, A, et al. Effect of Vertebroplasty on Pain Relief, Quality of Life, and the Incidence of New Vertebral Fractures: A 12-Month Randomized Follow-up, Controlled Trial. Journal of Bone and Mineral Research 2012; 27(5):1159–1166
11. Voormolen MHJ, Lohle PNM, Juttmann JR, et al. The Risk of New Osteoporotic Vertebral Compression Fractures in the Year after Percutaneous Vertebroplasty. Journal of Vascular and Interventional Radiology 2006; 17:71–76
12. Dhruv B. Pateder, A. Jay Khanna, Isador H. Lieberman. ‘Vertebroplasty and Kyphoplasty for the Management of Osteoporotic Vertebral Compression Fractures’ , Orthopedic Clinics of North America 2007; 38:409–418
13. Aparisi F. Vertebroplasty and Kyphoplasty in Vertebral Osteoporotic Fractures. Seminars in Musculoskeletical Radiology 2016; 20:382–391
14. He SC, Teng GJ, Deng G, et al. Repeat Vertebroplasty for Unrelieved Pain at Previously Treated Vertebral Levels With Osteoporotic Vertebral Compression Fractures. SPINE 2008; 33:640–647
15. Li X, Yang H, Tang T, et al. Comparison of Kyphoplasty and Vertebroplasty for Treatment of Painful Osteoporotic Vertebral Compression Fractures Twelve-month Follow-up in a Prospective Nonrandomized Comparative Study. Journal of Spinal Disorders and Techniques 2012; 25:142-149
16. Pradhan BB, Bae HW, Kropf MA, et al. Kyphoplasty Reduction of Osteoporotic Vertebral Compression Fractures: Correction of Local Kyphosis Versus Overall Sagittal Alignment. SPINE 2006; 31:435–441
17. Carlier RY, Gordji H, Mompoint DM, et al. Osteoporotic Vertebral Collapse: Percutaneous Vertebroplasty and Local Kyphosis Correction. Radiology 2004; 233:891–898
18. Rohlmann A, Zander T, Bergmann G. Spinal loads after osteoporotic vertebral fractures treated by vertebroplasty or kyphoplasty. European Spine Journal 2006 15: 1255–1264
19. Yuan WH., Hsu HC, Lai KL. Vertebroplasty and balloon kyphoplasty versus conservative treatment for osteoporotic vertebral compression fractures:A meta-analysis. Medicine 2016; 95:31
20. X R.V. Chandra, X J. Maingard, X H. Asadi, et al. Vertebroplasty and Kyphoplasty for Osteoporotic Vertebral Fractures: What Are the Latest Data? American Journal of Neuroradiology 2018; doi: 10.3174/ajnr.A5458 Epub 2017 Nov 23
21. Zhu RS, Kan SL, Ning GZ, et al. ‘Which is the best treatment of osteoporotic vertebral compression fractures: balloon kyphoplasty, percutaneous vertebroplasty, or non-surgical treatment? A Bayesian network meta-analysis’, Osteoporosis International 2019; doi: 10.1007 , Epub 2019 Jan 12
22. Kasperk C, Hillmeier J, Nöldge G, et al. Treatment of Painful Vertebral Fractures by Kyphoplasty in Patients With Primary Osteoporosis: A Prospective Nonrandomized Controlled Study. Journal of Bone and Mineral Research 2005; 20:604-612
23. Phillips FM. Minimally Invasive Treatments of Osteoporotic Vertebral Compression Fractures. SPINE 2003; 28(15S):S45–S53
24. Ates A, Gemalmaz HC, Deveci MA, et al. Comparison of effectiveness of kyphoplasty and vertebroplasty in patients with osteoporotic vertebra fractures. Acta Orthopaedica et Traumatologica Turcica 2016; doi: 10.1016/j/aott/2016.10.002
25. S. P. J. Muijs, A. R. van Erkel, P. D. S. Dijkstra Treatment of painful osteoporotic vertebral compression fractures: A brief review of the evidence for percutaneous vertebroplasty. The Journal of Bone and Joint Surgery 2011; 93-B:1149-53
Published
2022-03-24
Section
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