Pharmacological approach for the management of chronic low back pain

  • S. Papadokostaki
  • I. Vlamis
  • S.G. Pneumaticos
Keywords: chronic low back pain, medications, doses, effect


Chronic low back pain is a common condition affecting a high percentage of the general population. Affected people report diminished quality of life due to pain and disability. In terms of pharmacological treatment, physicians have a wide variety of options to choose from non-steroidal anti-inflammatory drugs (NSAIDS), opioids, non-opioids, muscle relaxants, antidepressants, antiepileptic drugs and biologic agents. However, there is no consensus as far as the optimal treatment is concerned.

A review of the current literature was performed to assess the efficacy and possible side effects of the different pharmacological treatments used in chronic low back pain and possibly give some guidelines about their use. The Pubmed and Cochrane databases were used to identify studies regarding the pharmacological treatment of chronic low back pain.


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Author Biographies

S. Papadokostaki

Postgraduate training program: “Rehabilitation following Spinal Cord lesions. Spinal Pain Management”, National and Kapodistrian University of Athens, KAT Hospital.

I. Vlamis

3rd Department of Orthopaedic Surgery NKUA, KAT, Hospital

S.G. Pneumaticos

3rd Department of Orthopaedic Surgery NKUA, KAT, Hospital


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