Infections of the spine: Current concepts and a literature review

  • Gavriil P. First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
  • Sioutis S. First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
  • Bekos A. First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
  • Gerasimides P. First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
  • Georgoulis J. First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
  • Soultanis K. First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
  • Mavrogenis A.F. First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
  • Sapkas G. First Department of Orthopaedics, National and Kapodistrian University of Athens, School of Medicine, ATTIKON University Hospital, Athens, Greece
Keywords: Spine Infections, Spondylitis, Spondylodiscitis, Pathogenesis, Clinical Presentation, Back pain

Abstract

Infections of the spine comprise a wide spectrum of different clinical manifestations depending on the exact anatomical structure involved. Spinal infections pose an essential health problem, the treatment of which requires a multidisciplinary approach. Diagnosis is based on clinical symptoms, radiologic evidence, laboratory tests and biopsy. The most common pathogens are bacteria; most of which spread hematogenously. Current treatment involves a combination of antibiotic agents. Sometimes, surgery is required to eradicate the infection or to treat its complications. In all cases, thorough and repetitive clinical examination and laboratory tests are of paramount importance for optimal outcomes.

 

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Published
2021-04-26